HIPPOCAMPAL ORNITHINE DECARBOXYLASE/SPERMIDINE PATHWAY MEDIATES H2S-ALLEVIATED COGNITIVE IMPAIRMENT IN DIABETIC RATS: INVOLVING ENHANCMENT OF HIPPOCAMPAL AUTOPHAGIC FLUX

Introduction: We have previously demonstrated the antagonistic role of hydrogen sulfide (H2S) in the cognitive dysfunction of streptozotocin (STZ)-induced diabetic rats.It has been confirmed that the impaired hippocampal autophagic flux has a key role in the pathogenesis of cognitive impairment and that ornithine decarboxylase (ODC)/spermidine (Spd

Abstract This Critical Synthesis Package contains: (1) a Critical Analysis of the psychometric properties and application to health sciences education for the Clinical Cultural Competency Questionnaire (CCCQ), and (2) a copy of the pretest version of the CCCQ developed by Bob Like, MD.The CCCQ measures physician knowledge, skills, attitudes, and co